Vitamin E and cancer prevention: Studies with different forms of tocopherols and tocotrienols
نویسندگان
چکیده
منابع مشابه
Tocopherols and tocotrienols as vitamin E
Introduction Vitamins are chemical compounds which are components of coenzymes and non-protein ingredients of enzymes. They are essential for life and normal functioning of the body. Vitamins are supplied with food as they cannot be synthesised by the body [1]. Bad diet, impaired vitamin absorption or the use of substances such as caffeine, nicotine and medicines may lead to hypovitaminosis, th...
متن کاملCancer prevention by different forms of tocopherols.
Many epidemiological studies have suggested that a low vitamin E nutritional status is associated with increased cancer risk. However, several recent large-scale human trials with high doses of α-tocopherol (α-T) have produced disappointing results. This points out the need for a better understanding of the biological activities of the different forms of tocopherols. Using a naturally occurring...
متن کاملVitamin E: tocopherols and tocotrienols as potential radiation countermeasures
Despite the potential devastating health consequences of intense total-body irradiation, and the decades of research, there still remains a dearth of safe and effective radiation countermeasures for emergency, radiological/nuclear contingencies that have been fully approved and sanctioned for use by the US FDA. Vitamin E is a well-known antioxidant, effective in scavenging free radicals generat...
متن کاملTowards the interaction mechanism of tocopherols and tocotrienols (vitamin E) with selected metabolizing enzymes
Vitamin E is a mixture of eight compounds alpha, beta, gamma, delta- tocopherols and alpha, beta, gamma, delta- tocotrienols. Their individual role in cellular transport as antioxidants and in metabolic pathways has been highlighted in the present work. All the eight compounds have been docked with the respective metabolizing enzymes (alpha-tocopherol transfer protein (ATTP), alpha-tocopherol a...
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در این مطالعه بر هم کنش این چهار کمپلکس با dna تیموس گوساله توسط روش های اسپکتروفتومتری، فلوریمتری، دو رنگ نمائی دورانی، و ویسکوزیمتری بررسی شدند تا اثر استخلاف های متیل بر روی لیگاندهای فنانترولین بررسی گردد.
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ژورنال
عنوان ژورنال: Molecular Carcinogenesis
سال: 2020
ISSN: 0899-1987,1098-2744
DOI: 10.1002/mc.23160